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|Pronunciation||/ t aɪ ˈ z æ n ɪ d iː n / tye- ZAN -i-deen|
|Trade names||Zanaflex, Sirdalud, and others|
|Routes of administration||By mouth (tablets, capsules)|
|ATC code||M03BX02 ( WHO )|
|Legal status||UK: POM (Prescription only) US: ℞-only|
|Metabolism||Liver (CYP1A2, 95%)|
|Elimination half-life||2.54 hours (tizanidine), 20–40 hours (inactive metabolites) |
|Excretion||Urine (60%), feces (20%)|
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The influence of hepatic impairment on the pharmacokinetics of tizanidine has not been evaluated. Because tizanidine is extensively metabolized in the liver, hepatic impairment would be expected zanaflex 10 mg have significant effects on pharmacokinetics of tizanidine.When my doctor suggested this medicine to me I made sure that it was not a narcotic and habit forming.
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I still woke with a headache but, the doctor said it won t change overnight. It will take time - to be patient.It is very zanaflex 10 mg acting though. It only lasts a couple of hours.
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It is important to emphasize that, although the events reported occurred during treatment with tizanidine, they were not necessarily caused by it.For comparison purposes, the corresponding frequency of the event per 100 patients among placebo treated patients is also provided.
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