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Seek medical advice if any new numbness, pain, skin color changes or reduced sensitivity occurs in fingers or toes. Sudden discontinuation has been associated with an exacerbation of angina, and sometimes myocardial infarction heart attack or ventricular arrhythmias.Elevated liver function test results, including reversible increases in serum aminotransferase labetalol hydrochloride 100 mg jaundice including labetalol hydrochloride 100 mg jaundice and hepatitis have been reported in patients receiving labetalol.

Severe hepatocellular injury, which has recurred during rechallenge, has occurred rarely during labetalol therapy; hepatocellular injury may be accompanied by clinical symptoms of hepatotoxicity, including pruritus, dark urine, persistent anorexia, jaundice, flu-like syndrome, and/or right upper quadrant tenderness.

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If the patient develops symptomatic bradycardia, then the dosage of labetalol should be reduced.g daily or higher administration of the drug in 3 divided doses daily may improve patient tolerance and/or facilitate dosage titration.

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These opinions do not represent the opinions of WebMD.If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away.

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Certain of the side effects increased with increasing dose, as shown in the following table that depicts labetalol hcl 100 mg entire U. therapeutic trials data base for adverse reactions that are clearly or possibly dose related.Birth Defects Res B Dev Reprod Toxicol.

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The clinical uses indicated in the labetalol hydrochloride 100 tablet represent both on and off-label uses of beta-blockers. For example, a given beta-blocker may only be approved by the FDA for treatment of hypertension; however, physicians sometimes elect to prescribe the drug for angina because of the class-action benefit that beta-blockers have for angina.Tell your doctor and pharmacist about any other medicines your child is taking before giving labetalol.

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The diluted solution should be administered at a rate of 2 mL/min to deliver 2 mg/min. Alternatively, the contents of two 20 mL vials 40 mL of Labetalol HCl labetalol hydrochloride 100 tablet are added to 250 mL of a commonly used intravenous fluid.atients should be advised not to discontinue labetalol hydrochloride 100 tablet without first consulting with the physician. n patients who experience an exacerbation of angina following discontinuation of beta-blocker therapy, the medication should generally be reinstituted, at least temporarily, along with other clinically appropriate measures.

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