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Clinical data | |
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Trade names | Cymbalta, others [1] |
AHFS/Drugs.com | Monograph |
MedlinePlus | a604030 |
License data | EU EMA: by INN, US FDA: duloxetine |
Pregnancy category | AU: B3 US: C (Risk not ruled out) |
Routes of administration | By mouth |
Drug class | Serotonin–norepinephrine reuptake inhibitor |
ATC code | N06AX21 ( WHO ) |
Legal status | |
Legal status | AU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only |
Pharmacokinetic data | |
Bioavailability | ~ 50% (32% to 80%) |
Protein binding | ~ 95% |
Metabolism | Liver, two P450 isozymes, CYP2D6 and CYP1A2 |
Elimination half-life | 12 hours |
Excretion | 70% in urine, 20% in feces |
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I take it for nerve pain, started with 30 mg now up to 90 mg a day. It s not helping much at all.eep all follow-up visits with the healthcare provider as scheduled.
Call the healthcare provider between visits as needed, especially if you have concerns about symptoms.
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I was functioning again and pain had lessened.Most people taking this medication do not experience any of these side effects. Disclose to your physician all mental health issues including any family history of suicide, bipolar disorder, mania, or depression.
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