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| Clinical data | |
|---|---|
| Trade names | Compro, others |
| AHFS/Drugs.com | Monograph |
| MedlinePlus | a682116 |
| Pregnancy category | C (Au, U.S.) |
| Routes of administration | By mouth, rectal, IM, IV |
| ATC code | N05AB04 ( WHO ) |
| Legal status | |
| Legal status | AU: S3 (Pharmacist only) UK: POM (Prescription only) but packs of 8 buccal tablets for nausea/vomiting associated with migraine are sold as pharmacy medicines, US: ℞-only |
| Pharmacokinetic data | |
| Bioavailability | Unknown, but presumed substantial |
| Protein binding | 91–99% |
| Metabolism | Mainly hepatic (CYP2D6 and/or CYP3A4) |
| Elimination half-life | 4–8 hours, differs with the method of administration |
| Excretion | Biliary, (colored) inactive metabolites in urine |
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